DIAZEPAM

DIAZEPAM
(Valium®…)

Prescription under medical supervision

Indications

– Anxiolytic, sedative, anticonvulsant, muscle relaxant
– Agitation and anxiety
– Muscle spasms
– 5 mg tablet

Also comes in 2 mg and 10 mg tablets and 1% oral solution.
– Child: 0.5 mg/kg/day in 3 divided doses
– Adult: 5 to 15 mg/day in 3 divided doses
– Do not exceed indicated doses.

Duration: according to clinical response ; the shortest duration possible.

Contra-indications, adverse effects, precautions

– Do not administer to patients with severe respiratory insufficiency or severe hepatic impairment.
– Administer only in exceptions and with caution to children.

– May cause:
   • feeling of inebriation, drowsiness (administer with caution when driving or operating
     machinery),
   • dependence and tolerance when used for more than 10-15 days. At the end of treatment,
     reduce doses gradually to avoid withdrawal syndrome or rebound effect.
   • in the event of overdose: ataxia, muscular weakness, hypotension, confusion, lethargy,
     respiratory depression, coma.

– Reduce the dose by one half in elderly patients and in patients with renal or hepatic impairment.

– Risk of increased sedation when combined with alcohol and drugs acting on the central
  nervous system: opioid analgesics, neuroleptics (chlorpromazine, haloperidol, etc.), anti-
  histamines (chlorphenamine, promethazine), antidepressants (clomipramine, fluoxetine,
  etc.), phenobarbital, etc.

– Pregnancy: avoid

– Breast-feeding: avoid

– Diazepam is subject to international controls: follow national regulations.

– Diazepam is not a treatment for depression, chronic anxiety, or post-traumatic stress syndrome.

– Storage: below 30°C –